Is your Gut Effecting your Weight Loss?

We sat down with Gastroenterologist, Dr. Alasdair Patrick, to explore one reason some people find it harder to lose weight than others — the gut microbiome. While many factors contribute to weight challenges, emerging research shows our gut bacteria may play a bigger role than we think.

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“Why is weight loss easier for some people than others?”

Dr. Patrick explains that it’s not always about willpower. Some people lose weight quickly and easily, while others struggle despite making consistent efforts. Emerging research suggests that your gut microbiome — the community of bacteria living in your digestive system — plays a key role. It may influence how your body stores fat, manages blood sugar, and signals hunger.

So, while many people can lose weight by eating fewer calories and choosing nutrient-rich foods, others may face added challenges due to imbalances in their gut flora. "If you're consuming fewer calories than you burn but still not losing weight, your gut microbiome could be part of the issue."

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“What role does gut biodiversity play in metabolism?”

Studies show that people who struggle with weight loss often have less gut microbial diversity compared to those who lose weight more easily. Increasing the diversity and volume of beneficial bacteria in your gut may help improve metabolic function and support weight management.

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“Why does your gut impact weight?”

Gut bacteria help digest food and, in doing so, release hormones known as Gut Peptides. These peptides send important signals to the brain related to hunger, digestion, and metabolism. Ensuring a balanced microbiome will improve the release of these hormones, which alters how efficiently your body burns energy instead of storing it.

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"How do Prebiotics help with weight loss?"

Prebiotics — like Alleviate — offer several powerful benefits for weight loss:

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1. Reduce hunger

Prebiotics promote the growth of good bacteria such as Bifidobacteria and Lactobacillus. When these bacteria ferment, they produce short-chain fatty acids (SCFAs), which release hormones like GLP-1s. This hormone — also mimicked in weight-loss medications like Ozempic — helps you feel full, slows gastric emptying, and balances blood sugar.

Fibre also helps with hunger because it moves slowly through the digestive tract - so you feel fuller for longer. One study found that taking an extra 14 grams of fibre a day led to a 10% reduction in calorie intake.

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2. Curb cravings

Prebiotics may also alter how the brain responds to high-calorie foods. They fuel beneficial gut bacteria, which send messages to our brain and influence our decision-making around food - reducing the "reward" signals triggered by junk food.

This means that when our microbiome is healthy, our brains are less tempted by high calorie foods.

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3. Boost metabolism

Prebiotics have also been shown to improve insulin sensitivity and increase energy expenditure, which helps enhance metabolic efficiency.

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4. Support fat reduction and nutrient absorption

Prebiotic fibres can reduce the amount of fat absorbed while also improving your body’s ability to absorb essential nutrients.

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5. Strengthen the gut barrier

Fibre can fortify the gut lining, which helps reduce inflammation and supports overall well-being.

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"Why Choose Alleviate?"

There’s no doubt that prebiotic fibre supports weight management — but not all fibres are equal. Partially Hydrolysed Guar Gum (PHGG) stands out in the research for its gut health and weight loss benefits.

In one study, women who added 15g of PHGG daily to a calorie-controlled diet lost 2.5kg more than those on a placebo.
Another study showed that just 2g of PHGG per day significantly reduced hunger and cut snacking by 20%.

With regular use, Alleviate supports a healthier gut, increases biodiversity, may reduce cravings for high-calorie foods, manage hunger, balance blood sugar, and boost metabolic efficiency. "It’s a valuable addition to any weight loss programme, especially if you've found it difficult to lose weight or maintain results."